Toxic Non-Metal Chemical Exposure-Urine


Testing offered by Mosaic Diagnostics (formerly The Great Plains Laboratory): A toxic non-metal chemical profile that screens for the presence of 173 different toxic chemicals with a urine test.


Every day, we are exposed to hundreds of toxic chemicals through products like pharmaceuticals, pesticides, packaged foods, household products, and environmental pollution.  As we have become more exposed to chemical-laden products and to toxic chemicals in food, air, and water, we have been confronted with an accelerating rate of chronic illnesses like cancer, heart disease, chronic fatigue syndrome, chemical sensitivity, autism spectrum disorders, ADD/AD(H)D, autoimmune disorders, Parkinson’s disease, and Alzheimer’s disease.

Because exposure to environmental pollutants has been linked to many chronic diseases, Mosaic Diagnostics (formerly The Great Plains Laboratory) has created GPL-TOX, a toxic non-metal chemical profile that screens for the presence of 173 different toxic chemicals including organophosphate pesticides, phthalates, benzene, xylene, vinyl chloride, pyrethroid insecticides, acrylamide, perchlorate, diphenyl phosphate, ethylene oxide, acrylonitrile, and more.  This profile also includes Tiglylglycine (TG), a marker for mitochondrial disorders resulting from mutations of mitochondrial DNA.  These mutations can be caused by exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies.

Sample Report

Test Brochure


  • GPL-TOX screens for 173 different environmental pollutants using 18 different metabolites, all from a single urine sample.
  • GPL-TOX uses the power of advanced mass spectrometry (MS/MS), which is necessary to detect lower levels of certain genetic, mitochondrial, and toxic chemical markers that conventional mass spectrometry often misses.
  • GPL-TOX also includes Tiglylglycine, a marker for mitochondrial damage, which is often seen in chronic toxic chemical exposure.
  • GPL-TOX pairs perfectly with our Organic Acids Test (OAT) and our Glyphosate Test in the Enviro-TOX Panel. This panel offers you comprehensive testing to assess exposure to common environmental toxins and the damage that can be caused by this exposure, all at a great value, and all from one urine sample.

Turnaround time for results is 1-3 weeks from the time your specimen is received.

All Orders Receive:

  • Test kit shipped directly to the address of your choosing.
  • Step-by-step test collection instructions.
  • Email support from IOE Program within 24 hours to confirm shipping address.
  • Prepaid shipping label for the submission of a sample.
  • Written report that summarizes all test findings emailed to you as a PDF file.
  • The option to receive additional insight into these findings by Dr. Lawenda. **Requires additional purchase of a lab review. Not automatically included. 

**NEW YORK RESIDENTS: Restrictions apply. If you are interested in this test, please reach out to us by emailing before ordering.

**INTERNATIONAL ORDERS:  Restrictions apply. Please contact us to confirm availability by emailing Testing not available in all areas outside of U.S.**


  • Alzheimer’s Disease

  • Amyotrophic Lacteroclerosis (ALS)

  • Anorexia Nervosa

  • Anxiety Disorder

  • Apraxia

  • Arthritis

  • Asthma

  • Attention deficit (ADD)

  • Attention deficit with hyperactivity (ADHD)

  • Autism

  • Autoimmune disorders

  • Bipolar disorder

  • Cancer

  • Cerebral palsy

  • Chronic fatigue syndrome

  • Crohn’s disease

  • Depression

  • Developmental disorder

  • Down Syndrome

  • Epilepsy

  • Failure to thrive

  • Fibromyalgia

  • Genetic diseases

  • Irritable bowel syndrome

  • Learning disability

  • Mitochondria disorder

  • Multiple sclerosis

  • Obsessive compulsive disorder (OCD)

  • Occupational exposures

  • Parkinson’s disease

  • Peripheral neuropathy

  • Schizophrenia

  • Seizure disorders

  • Systemic lupus erythematosus

  • Tic disorders

  • Tourette syndrome

  • Ulcerative colitis

More Information